MORE COMMON IMMUNE-SYSTEM DISEASES: SARCOIDOSIS AND SCLERODERMA

SARCOIDOSIS: we don’t know what causes it; possibly a virus.

Signs and Symptoms: may be fever; pains in joints; generalized body aches; cough; weight loss. Can have shortness of breath, lumps on the skin; enlarged liver; inflammation of a portion of the eye, which can lead to glaucoma and loss of vision. May get into heart and cause chest pain. Usually gets into lungs, causing shortness of breath. Many times I have made the diagnosis of sarcoidosis from the characteristic appearance of the X-ray, which shows enlarged lymph glands in the chest.

SCLERODERMA (progressive systemic sclerosis): chronic disease with generalized fibrosis (thickening) of the skin, joints and many internal organs.

Signs and Symptoms: joint pains; stomach upsets; heartburn; weight loss; malaise; difficulty in swallowing; shortness of breath. Skin of fingers and face becomes thick. Normal creases on the fingers and face disappear. Fingers become purple and hurt when exposed to cold. Face become thick, like a mask, and blood vessels on face, lips and tongue become prominent. Other symptoms may be esophogitis; (inflamations of the esophagus); pleurisy; pericarditis (inflammation of the sac surrounding the heart); heart irregularities; muscle weakness. Death from pneumonia often occurs.

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