For both men and women, antifungal medications provide dependable treatment for yeast infections. Men usually have success with over-the-counter creams applied to the affected area twice a day for two weeks. Treatment with antifungal medication is recommended only for a woman with symptoms, and then only for a woman who has been diagnosed with yeast infection in the past and is certain that yeast is again the cause of her symptoms. For women, there is no reason to treat yeast colonization if it is not causing symptoms.
Many antifungal creams are available without a prescription, and most of them are well tolerated, except for the rare allergic reaction. Since all over-the-counter creams are equally effective (they cure infection 80-90 percent of the time), using the least expensive cream seems to make sense. Butoconazole, clotrimazole, miconazole, and tioconazole are some of the most frequently used medications; they are applied at night, some as a single dose, some for three days, and some for a week.
Women can use either creams, which are inserted into the vagina with an applicator packaged with the cream, or vaginal suppositories, which are pills that are inserted into the vagina. When using a cream, for best results the medication should be rubbed on the vulva (the outside of the genitals) as well as inserted into the vagina. For women with a history of difficult, recurrent yeast infections, the longer, seven-day course is a better option from the start. Some women experience irritation from the frequent use of the treatments themselves, and in this case an alternative treatment (see the next paragraph) should be used. Because the creams are oil based, they may weaken latex condoms and diaphragms.
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